Ex 26 | Tocris Bioscience 5833/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ex 26

catalog :

5833/10

quantity :

10 mg (also 50 mg)

price :

214 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5833

SKU :

5833/10

rank :

0.0006

product name :

Ex 26

description :

Potent and selective S1P1 receptor antagonist

target :

Sphingosine-1-phosphate Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ex 26 is a potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM). Exhibits 3,000-fold selectivity for S1P1 over S1P2, S1P3, S1P4 and S1P5. Induces lymphocyte sequestration in peripheral lymph nodes and upregulates S1P1 receptor expression. Reduces disease severity in mice with EAE. Increases IFN- production in stimulated dendritic cells in vivo .

extended description :

Potent and selective S1P1 receptor antagonist

chemical name text :

1-[[[5 -[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2 -fluoro-3,5-dimethyl[1,1 -biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid

formula :

C 28 H 28 ClFN 2 O 3

formula text :

C28H28ClFN2O3

cas num :

1233332-37-0

USD :

214 USD

product details :

Potent and selective S1P1 receptor antagonist

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage