TGX 221 | Tocris Bioscience 5832/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TGX 221

catalog :

5832/10

quantity :

10 mg (also 50 mg)

price :

321 USD

citations: 1

Reference
Blair T, Moore S, Walsh T, Hutchinson J, Durrant T, Anderson K, et al. Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation. Cell Signal. 2018;50:111-120 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5832

SKU :

5832/10

product name :

TGX 221

description :

Potent and selective PI 3-kinase inhibitor

target :

PI 3-Kinase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

364.44

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TGX 221 is a potent and selective PI 3-kinase inhibitor (IC50 values are 0.007, 0.1, 3.5 and 5 M for the , , and isoforms, respectively). Shows 1,000-fold selectively for PI 3-kinase over a range of other kinases. Inhibits thrombus formation in animal models.

product keywords :

TGX221 PI3K PI 3-kinase phosphoinositide potent selective inhibits inhibitors beta antithrombotic PI 3-Kinase 5832,

extended description :

Potent and selective PI 3-kinase inhibitor

chemical name text :

7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one

formula :

C21H24N4O2

formula text :

C21H24N4O2

cas num :

663619-89-4

USD :

356

USD 2025 :

321 USD

product details :

Potent and selective PI 3-kinase inhibitor