chemical

C-DIM 12

5821

10 mg (also 50 mg)

138 USD

5821

5821/10

C-DIM 12

Nurr1 activator; inhibits NF- B-dependent gene expression

Nuclear Receptor Agonists

Small Molecules

10 mg (also 50 mg)

98%

356.85

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Nurr1 activator. Inhibits NF- B and cytokine expression in microglial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters. Neuroprotective in a mouse Parkinson s disease model. Orally bioavailable.

5821

C-DIM12 Nurr1 activators activates NF-KB NK-kappaB NF- B signaling signalling orally bioavailable neuroprotective neuroinflammation NF-kB/IkB Nerve Growth Factor IB-like Receptors 5821,

Nurr1 activator; inhibits NF- B-dependent gene expression

3,3 -[(4-Chlorophenyl)methylene]bis[1H-indole]

C 23 H 17 ClN 2

C23H17ClN2

178946-89-9

138

138 USD

Store at -20°C