Bexarotene | Tocris Bioscience 5819 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Bexarotene

catalog :

5819

quantity :

10 mg (also 50 mg)

price :

75 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
McCullough K, Daskalakis N, Gafford G, Morrison F, Ressler K. Cell-type-specific interrogation of CeA Drd2 neurons to identify targets for pharmacological modulation of fear extinction. Transl Psychiatry. 2018;8:164 pubmed publisher
Hebert S, Fitzpatrick K, McConnell S, Cucak A, Yuan C, McLoon L. Effects of retinoic acid signaling on extraocular muscle myogenic precursor cells in vitro. Exp Cell Res. 2017;361:101-111 pubmed publisher

product information

brand :

Tocris

master code :

5819

SKU :

5819/10

product name :

Bexarotene

description :

Potent and selective RXR agonist

target :

Retinoid X Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

348.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective RXR agonist (EC50 values are 24, 25 and 33 nM for RXR , RXR and RXR , respectively). Exhibits 300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro , and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts.

catalog number base :

5819

product keywords :

retinoid X receptors agonists agonism RXR alpha beta gamma potent selective cancer metastasis angiogenesis LG1069 stem cells differentiation brown adipocytes adipogenic reprogramming LGD1069 Retinoid X Receptor Stem Cell Reprogramming 5819,

extended description :

Potent and selective RXR agonist

chemical name text :

4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid

formula :

C 24 H 28 O 2

formula text :

C24H28O2

cas num :

153559-49-0

2020 USD :

2021 USD :

75 USD

alt names :

LGD 1069

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage