Bexarotene | Tocris Bioscience 5819/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Bexarotene

catalog :

5819/10

quantity :

10 mg (also 50 mg)

price :

88 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
McCullough K, Daskalakis N, Gafford G, Morrison F, Ressler K. Cell-type-specific interrogation of CeA Drd2 neurons to identify targets for pharmacological modulation of fear extinction. Transl Psychiatry. 2018;8:164 pubmed publisher
Hebert S, Fitzpatrick K, McConnell S, Cucak A, Yuan C, McLoon L. Effects of retinoic acid signaling on extraocular muscle myogenic precursor cells in vitro. Exp Cell Res. 2017;361:101-111 pubmed publisher

product information

brand :

Tocris

master code :

5819

SKU :

5819/10

rank :

0.061

product name :

Bexarotene

description :

Potent and selective RXR agonist

target :

Retinoid X Receptor Agonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Bexarotene is a potent and selective RXR agonist (EC50 values are 24, 25 and 33 nM for RXR , RXR and RXR , respectively). Exhibits 300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro , and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts.

extended description :

Potent and selective RXR agonist

chemical name text :

4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid

formula :

C 24 H 28 O 2

formula text :

C24H28O2

cas num :

153559-49-0

USD :

88 USD

product details :

Potent and selective RXR agonist

alt names :

LGD 1069

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage