product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
M 084 hydrochloride
catalog :
5807/10
quantity :
10 mg (also 50 mg)
price :
105 USD
more info or order :
citations: 2
Reference
Amores Bonet L, Kleene R, Theis T, Schachner M. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ into Neurons. Int J Mol Sci. 2022;23: pubmed publisher
Cai Y, Ford C. Dopamine Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of Dopamine and Glutamate. Cell Rep. 2018;25:3148-3157.e3 pubmed publisher
image
image 1 :
Tocris Bioscience 5807/10 image 1
Cat.No. 5807 - M 084 hydrochloride C11H15N3.HCl CAS No. 1992047-63-8
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
5807
SKU :
5807/10
product name :
M 084 hydrochloride
description :
TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic
target :
TRPC Channel Blockers
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Desiccate at RT
observed molecular weight :
225.72
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
M 084 hydrochloride is a TRPC4/5 channel blocker (IC50 values are 3.7-10.3 and 8.2 M, respectively). Also weakly blocks TRPC3 channels. Exhibits rapid antidepressant and anxiolytic effects in vivo .
product keywords :
M084 hydrochloride TRPC4/5 blockers inhibitors inhibits transient receptor potential channels canonical TRPC TRPC 5807,
extended description :
TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic
chemical name text :
N-Butyl-1H-benzimidazol-2-amine hydrochloride
formula :
C11H15N3.HCl
formula text :
C11H15N3.HCl
cas num :
1992047-63-8
USD :
103
USD 2025 :
105 USD
product details :
TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK