Mitoglitazone | Tocris Bioscience 5799 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Mitoglitazone

catalog :

5799

quantity :

10 mg (also 50 mg)

price :

164 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5799

SKU :

5799/10

product name :

Mitoglitazone

description :

Insulin sensitizer; exhibits low binding affinity at PPAR

target :

Additional Insulin and Insulin-like Receptor Product

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

370.42

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Insulin sensitizer; enhances insulin sensitivity and lowers blood-glucose levels in diabetic mouse models. Inhibits mitochondria pyruvate carriers; increases mitochondrial respiration rates, leading to a reduction in expression of lipogenic enzymes. Suppresses gluconeogenesis and lipogenesis in primary hepatocytes. Exhibits low binding affinity and activity at PPAR (EC50 = 23.7 M).

catalog number base :

5799

product keywords :

Antidiabetic neurodegeneration Alzheimer's Parkinson's diseases mTOT target thiazolidinones insulin resistance mitochondria metabolism pyruvate carriers MPC hyperglycemia CAY 10415 MSDC 0160 Insulin and insulin-like Receptors Insulin and Insulin-like Receptors PPARgamma Receptors 5799, Additional Insulin and Insulin-like Receptor Products

extended description :

Insulin sensitizer; exhibits low binding affinity at PPAR

chemical name text :

5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione

formula :

C 19 H 18 N 2 O 4 S

formula text :

C19H18N2O4S

cas num :

146062-49-9

2020 USD :

164

2021 USD :

164 USD

alt names :

CAY 10415, MSDC 0160

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage