LM 10 | Tocris Bioscience 5794 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LM 10

catalog :

5794

quantity :

10 mg (also 50 mg)

price :

94 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5794

SKU :

5794/10

product name :

LM 10

description :

Selective tryptophan 2,3-dioxygenase (TDO) inhibitor

target :

Tryptophan 2,3 Dioxygenase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

229.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 M for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.

catalog number base :

5794

product keywords :

LM10 selective 2,3-dioxygenase TDO inhibitors inhibits orally bioavailable anticancer cancer immunology Tryptophan 2,3 dioxygenase Immune Checkpoints 5794,

extended description :

Selective tryptophan 2,3-dioxygenase (TDO) inhibitor

chemical name text :

6-Fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole

formula :

C 11 H 8 FN 5

formula text :

C11H8FN5

cas num :

1316695-35-8

2020 USD :

2021 USD :

94 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage