product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Bz 423
catalog :
5791
quantity :
10 mg (also 50 mg)
price :
160 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
5791
SKU :
5791/10
product name :
Bz 423
description :
ATP synthase inhibitor; proapoptotic
target :
Synthase/Synthetase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
440.92
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ATP synthase inhibitor (IC50 5 M). Binds the oligomycin sensitivity conferring protein (OSCP) component of mitochondrial F1F0-ATPase in vitro resulting in generation of superoxide and apoptosis. Kills primary B and T cell in mice in vivo . Suppresses autoimmunity and prolongs survival in mouse lupus model.
catalog number base :
5791
product keywords :
Bz423 ATP synthase inhibitors inhibits pro-apoptotic oligomycin sensitivity conferring protein OSCP autoimmunity superoxide generation Other Synthases/Synthetases Apoptosis Inducers 5791,
extended description :
ATP synthase inhibitor; proapoptotic
chemical name text :
7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one
formula :
C 27 H 21 ClN 2 O 2
formula text :
C27H21ClN2O2
cas num :
216691-95-1
2020 USD :
155
2021 USD :
160 USD
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK