PF 05175157 | Tocris Bioscience 5790 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 05175157

catalog :

5790

quantity :

10 mg (also 50 mg)

price :

170 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5790

SKU :

5790/10

product name :

PF 05175157

description :

Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

target :

Additional Lipid Metabolism Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

405.49

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Acetyl-CoA carboxylase (ACC) 2 and 1 inhibitor (IC50 values are 45 and 98 nM, respectively). Reduces hepatic and skeletal muscle malonyl-CoA levels in rats. Also inhibits hepatic de novo lipogenesis and reduces whole body respiratory exchange ratio in rats. Orally bioavailable.

catalog number base :

5790

product keywords :

PF05175157 Acetyl CoA carboxylase 1 2 inhibitors inhibits ACC1 ACC2 orally bioavailable type 2 diabetes mellitus Other Ligases Other Lipid Metabolism 5790,

extended description :

Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

chemical name text :

1,4-Dihydro-1 -[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4 -piperidin]-7(6H)-one

formula :

C 23 H 27 N 5 O 2

formula text :

C23H27N5O2

cas num :

1301214-47-0

2020 USD :

163

2021 USD :

170 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage