PF 05175157 | Tocris Bioscience 5790/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 05175157

catalog :

5790/10

quantity :

10 mg (also 50 mg)

price :

214 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lien E, Westermark A, Zhang Y, Yuan C, Li Z, Lau A, et al. Low glycaemic diets alter lipid metabolism to influence tumour growth. Nature. 2021;599:302-307 pubmed publisher

image

image 1 :

Cat.No. 5790 - PF 05175157 C23H27N5O2 CAS No. 1301214-47-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5790

SKU :

5790/10

product name :

PF 05175157

description :

Potent acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

target :

Additional Lipid Metabolism Compounds

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

405.49

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PF 05175157 is an potent acetyl-CoA carboxylase (ACC) 2 and 1 inhibitor (IC50 values are 45 and 98 nM, respectively). Reduces hepatic and skeletal muscle malonyl-CoA levels in rats. Also inhibits hepatic de novo lipogenesis and reduces whole body respiratory exchange ratio in rats. Orally bioavailable.

product keywords :

PF05175157 Acetyl CoA carboxylase 1 2 inhibitors inhibits ACC1 ACC2 potent orally bioavailable type 2 diabetes mellitus Other Ligases Other Lipid Metabolism 5790,

extended description :

Potent acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

chemical name text :

1,4-Dihydro-1 -[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4 -piperidin]-7(6H)-one

formula :

C23H27N5O2

formula text :

C23H27N5O2

cas num :

1301214-47-0

USD :

211

USD 2025 :

214 USD

product details :

Potent acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

more info or order :

Tocris Bioscience product webpage