DEL 22379 | Tocris Bioscience 5774/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DEL 22379

catalog :

5774/10

quantity :

10 mg (also 50 mg)

price :

223 USD

citations: 1

Reference
Schinzel R, Higuchi Sanabria R, Shalem O, Moehle E, Webster B, Joe L, et al. The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER. Cell. 2019;179:1306-1318.e18 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5774

SKU :

5774/10

product name :

DEL 22379

description :

ERK dimerization inhibitor

target :

ERK Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

444.53

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DEL 22379 is an ERK dimerization inhibitor (IC50 ~ 0.5 M); inhibits ERK dimerization without affecting phosphorylation or kinase activity. Suppresses growth of tumor cells expressing RAS-ERK oncogenes in vitro . Induces apoptosis and prevents tumor progression in vivo .

product keywords :

ERK dimerization inhibitors inhibits extracellular signal related kinase RAS ERK 5774, extracellular signal-regulated kinase, inhibitor, inhibition, ERK inhibition

extended description :

ERK dimerization inhibitor

chemical name text :

N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide

formula :

C26H28N4O3

formula text :

C26H28N4O3

cas num :

181223-80-3

USD :

247

USD 2025 :

223 USD

product details :

ERK dimerization inhibitor