HS 38 | Tocris Bioscience 5768 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HS 38

catalog :

5768

quantity :

5 mg

price :

80 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5768

SKU :

5768/5

product name :

HS 38

description :

ATP-competitive inhibitor of DAPK and ZIPK

target :

Death-associated Protein Kinase (DAPK) Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

349.8

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ATP-competitive inhibitor of DAPK (IC50 = 200 nM) and ZIPK (Kd = 280 nM). Also inhibits PIM3 kinase (IC50 = 200 nM) but exhibits no significant effect on Src or Abl kinases. Reduces phosphorylation of regulatory myosin light chain and myosin light chain phosphatase in mouse aortic and rabbit ileal tissues.

catalog number base :

5768

product keywords :

HS38 ATP-competitive inhibitors inhibits DAPK ZIPK PIM3 kinase regulatory myosin light chain myosin llight chain phosphatase DAPK 5768, DAPK Inhibitors, DAPK Inhibitor

extended description :

ATP-competitive inhibitor of DAPK and ZIPK

chemical name text :

2-[[1-(3-Chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]propanamide

formula :

C 14 H 12 CIN 5 O 2 S

formula text :

C14H12ClN5O2S

cas num :

1030203-81-6

2020 USD :

2021 USD :

80 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage