A 971432 | Tocris Bioscience 5766/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

A 971432

catalog :

5766/10

quantity :

10 mg (also 50 mg)

price :

188 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Matsushima Nishiwaki R, Yamada N, Fukuchi K, Kozawa O. Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2. PLoS ONE. 2018;13:e0209050 pubmed publisher

image

image 1 :

Cat.No. 5766 - A 971432 C18H17Cl2NO3 CAS No. 1240308-45-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5766

SKU :

5766/10

product name :

A 971432

description :

Potent and selective S1P5 agonist

target :

Sphingosine-1-phosphate Receptor Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at RT

observed molecular weight :

366.24

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A 971432 is a potent and selective S1P5 agonist (EC50 values are 4.1 and 5.7 nM in cAMP and GTP S assays, respectively). Exhibits 60-fold selectivity over S1P1, and 1,600-fold selectivity over S1P2-4, and a panel of 129 kinases and 79 receptors. Improves blood-brain barrier integrity in vitro and reverses age-related cognitive decline in vivo . Orally available.

product keywords :

A971432 potent selective S1P5 sphingosine phosphate receptors neurodegeneration orally bioavailable blood-brain barrier Sphingosine-1-phosphate Receptors 5766,

extended description :

Potent and selective S1P5 agonist

chemical name text :

1-[[4-[(3,4-Dichlorophenyl)methoxy]phenyl]methyl]-3-azetidinecarboxylic acid

formula :

C18H17Cl2NO3

formula text :

C18H17Cl2NO3

cas num :

1240308-45-5

USD :

186

USD 2025 :

188 USD

product details :

Potent and selective S1P5 agonist

more info or order :

Tocris Bioscience product webpage