AGN 193109 | Tocris Bioscience 5758/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AGN 193109

catalog :

5758/10

quantity :

10 mg

price :

355 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Moreau C, Caldarelli P, Rocancourt D, Roussel J, Denans N, Pourquie O, et al. Timed Collinear Activation of Hox Genes during Gastrulation Controls the Avian Forelimb Position. Curr Biol. 2019;29:35-50.e4 pubmed publisher
Jian Z, Cheng T, Zhang Z, Raulefs S, Shi K, Steiger K, et al. Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma. Cell Mol Gastroenterol Hepatol. 2018;6:429-449 pubmed publisher
Blixt M, Konjusha D, Ring H, Hallböök F. The zinc finger gene Nolz1 regulates the formation of retinal progenitor cells and suppresses the Lim3/Lhx3 phenotype of retinal bipolar cells in chicken retina. Dev Dyn. 2017;: pubmed publisher

product information

brand :

Tocris

master code :

5758

SKU :

5758/10

rank :

0.0006

product name :

AGN 193109

description :

High affinity pan-RAR antagonist

target :

Retinoic Acid Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AGN 193109 is a high affinity pan-retinoic acid receptor (RAR) antagonist (Kd values are 2, 2 and 3 nM at RAR , RAR and RAR , respectively). Exhibits no significant affinity for retinoic X receptors. AGN 193109 promotes the differentiation from mouse embryonic stem cells into paraxial mesoderm. AGN 193109 suppresses primary human cardiovascular smooth muscle cell calcification. . AGN 193109 synthesized to Ancillary Material Grade also available.

extended description :

High affinity pan-RAR antagonist

chemical name text :

4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid

formula :

C 28 H 24 O 2

formula text :

C28H24O2

cas num :

171746-21-7

USD :

355 USD

product details :

High affinity pan-RAR antagonist

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage