Tariquidar dihydrochloride | Tocris Bioscience 5757 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Tariquidar dihydrochloride

catalog :

5757

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5757

SKU :

5757/10

product name :

Tariquidar dihydrochloride

description :

Potent P-glycoprotein (P-gp) inhibitor

target :

Multidrug Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

719.66

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent P-glycoprotein (P-gp) inhibitor (IC50 = 5.1 nM). Reverses drug resistance in multiple MDR cell lines. Acts as a substrate for breast cancer resistance protein (BCRP) at low concentrations and acts as an inhibitor of BCRP when used at 100 nM concentration. Potentiates the cytotoxic effects of doxorubicin (Cat. No. 2252) and mitoxantrone (Cat. No. 4250) in vitro .

catalog number base :

5757

product keywords :

Potent P-glycoprotein P-gp inhibitors inhibits multidrug resistance MDR breast cancer resistant protein BCRP substrates cytotoxic abcb1 atp binding cassette 206873-63-4 Multidrug Transporters 5757,

extended description :

Potent P-glycoprotein (P-gp) inhibitor

chemical name text :

N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride

formula :

C 38 H 38 N 4 O 6 .2HCl

formula text :

C38H38N4O6.2HCl

cas num :

1992047-62-7

2020 USD :

197

2021 USD :

205 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage