MLi-2 | Tocris Bioscience 5756/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MLi-2

catalog :

5756/10

quantity :

10 mg (also 50 mg)

price :

323 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Henderson M, Peng C, Trojanowski J, Lee V. LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons. Acta Neuropathol Commun. 2018;6:45 pubmed publisher

product information

brand :

Tocris

master code :

5756

SKU :

5756/10

rank :

0.0006

product name :

MLi-2

description :

Potent and selective LRRK2 inhibitor

target :

LRRK2 Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MLi-2 is a potent and selective LRRK2 inhibitor (IC50 = 0.76-3.4 nM depending on assay), which exhibits 295-fold selectivity for over 300 kinases and a diverse panel of receptors and ion channels. MLi-2 is centrally bioavailable and active in vivo .

extended description :

Potent and selective LRRK2 inhibitor

chemical name text :

rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole

formula :

C 21 H 25 N 5 O 2

formula text :

C21H25N5O2

cas num :

1627091-47-7

USD :

323 USD

product details :

Potent and selective LRRK2 inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage