PF 06260933 dihydrochloride | Tocris Bioscience 5752/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 06260933 dihydrochloride

catalog :

5752/10

quantity :

10 mg (also 50 mg)

price :

210 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gao X, Chen G, Gao C, Zhang D, Kuan S, Stabile L, et al. MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance. Mol Oncol. 2017;11:628-639 pubmed publisher

product information

brand :

Tocris

master code :

5752

SKU :

5752/10

rank :

0.061

product name :

PF 06260933 dihydrochloride

description :

MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK

target :

HGK

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PF 06260933 dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). Also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). Improves fasting hyperglycemia in mice. Orally active.

extended description :

MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK

chemical name text :

5-(4-Chlorophenyl)-[3,3 -bipyridine]-6,6 -diamine dihydrochloride

formula :

C 16 H 13 ClN 4 .2HCl

formula text :

C16H13ClN4.2HCl

cas num :

1883548-86-4

USD :

210 USD

product details :

MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK

alt names :

EC 2.7.11, EC 2.7.11.1, FLH21957, FLJ10410, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, HGKFLJ20373, HPK/GCK-like kinase HGK, KIAA0687, MAP4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, mitogen-activated protein kinase kinase kinase kinase 4, Nck-interacting kinase, NIKFLJ90111

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage