25-Hydroxycholesterol | Tocris Bioscience 5741/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

25-Hydroxycholesterol

catalog :

5741/10

quantity :

10 mg

price :

124 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Limbad C, Doi R, McGirr J, Ciotlos S, Perez K, Clayton Z, et al. Senolysis induced by 25-hydroxycholesterol targets CRYAB in multiple cell types. iScience. 2022;25:103848 pubmed publisher
Alice A, Kramer G, Bambina S, Bahjat K, Gough M, Crittenden M. Listeria monocytogenes-infected human monocytic derived dendritic cells activate Vγ9Vδ2 T cells independently of HMBPP production. Sci Rep. 2021;11:16347 pubmed publisher

image

image 1 :

Cat.No. 5741 - 25-Hydroxycholesterol C27H46O2 CAS No. 2140-46-7

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5741

SKU :

5741/10

product name :

25-Hydroxycholesterol

description :

Inhibits hepatitis C viral life cycle; also -crystallin (cryAB) chaperone

target :

Antiviral Compounds

unit size :

10 mg

category :

Small Molecules

purity :

95%

storage :

Store at -20°C

observed molecular weight :

402.65

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

25-Hydroxycholesterol is an antiviral. Stimulates expression of miR-185 microRNA which inhibits the hepatitis C virus life cycle via inhibition of cholesterol biosynthesis and virus cell membrane fusion. Also -crystallin (cryAB) chaperone (Kd = 10.1 M). Blocks -crystallin aggregation and partially reverses cataract formation by binding and stabilizing soluble forms of cryAB in vitro and in vivo .

product keywords :

Antiviral alpha-crystallin chaperone a-crystallin -crystallin microRNA miR-185 hepatitis C virus HCV cholesterol aggregation cataract cryAB cryAA amyloid Hepatitis Viruses 5741,

extended description :

Inhibits hepatitis C viral life cycle; also -crystallin (cryAB) chaperone

chemical name text :

Cholest-5-ene-3 ,25-diol

formula :

C27H46O2

formula text :

C27H46O2

cas num :

2140-46-7

USD :

119

USD 2025 :

124 USD

product details :

Inhibits hepatitis C viral life cycle; also -crystallin (cryAB) chaperone

more info or order :

Tocris Bioscience product webpage