This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
A 127722
catalog :
5730/10
quantity :
10 mg
price :
186 USD
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
5730
SKU :
5730/10
product name :
A 127722
description :
Highly potent, selective ETA antagonist; orally bioavailable
target :
Endothelin ETA Receptor Antagonists
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
510.62
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
A 127722 is a highly potent and selective ETA endothelin receptor antagonist (IC50 values are 0.11 nM and 98 nM for human ETA and ETB receptors, respectively). Attenuates hypoxia-induced pulmonary hypertension in rats. Orally bioavailable.
product keywords :
A127722 Endothelin receptor A ETA antagonists potent selective Endothelin ETA Receptors 5730,
extended description :
Highly potent, selective ETA antagonist; orally bioavailable
chemical name text :
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid
formula :
C29H38N2O6
formula text :
C29H38N2O6
cas num :
195704-72-4
USD :
206
USD 2025 :
186 USD
product details :
Highly potent, selective ETA antagonist; orally bioavailable
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK