TASP 0390325 | Tocris Bioscience 5729 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TASP 0390325

catalog :

5729

quantity :

10 mg (also 50 mg)

price :

221 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Campos Lira E, Kelly L, Seifi M, Jackson T, Giesecke T, Mutig K, et al. Dynamic Modulation of Mouse Locus Coeruleus Neurons by Vasopressin 1a and 1b Receptors. Front Neurosci. 2018;12:919 pubmed publisher

product information

brand :

Tocris

master code :

5729

SKU :

5729/10

product name :

TASP 0390325

description :

Potent and selective V1B receptor antagonist; orally bioavailable

target :

Vasopressin Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

554.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective V1B receptor antagonist (IC50 = 2.22 nM for rat pituitary receptor). Exhibits no significant affinity for 85 other receptors, ion channels and transporters at 10 M, including V1A and V2. Increases ACTH levels in rats. Orally bioavailable. Antidepressant and anxiolytic.

catalog number base :

5729

product keywords :

TASP0390325 vasopressin receptors antagonists antagonism potent selective V1B anxiolytic antidepressant Vasopressin Receptors 5729,

extended description :

Potent and selective V1B receptor antagonist; orally bioavailable

chemical name text :

2-(3-Chloro-4-fluorophenyl)-N-(1-methylethyl)-6-[3-(4-morpholinyl)propoxy]-4-oxo-pyrido[2,3-d]pyrimidine-3(4H)-acetamide hydrochloride

formula :

C 25 H 29 ClFN 5 O 4 .HCl

formula text :

C25H29ClFN5O4.HCl

cas num :

1642187-96-9

2020 USD :

214

2021 USD :

221 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage