TASP 0390325 | Tocris Bioscience 5729/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TASP 0390325

catalog :

5729/10

quantity :

10 mg (also 50 mg)

price :

278 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Campos Lira E, Kelly L, Seifi M, Jackson T, Giesecke T, Mutig K, et al. Dynamic Modulation of Mouse Locus Coeruleus Neurons by Vasopressin 1a and 1b Receptors. Front Neurosci. 2018;12:919 pubmed publisher

image

image 1 :

Cat.No. 5729 - TASP 0390325 C25H29ClFN5O4.HCl CAS No. 1642187-96-9

product information

brand :

Tocris

catalog number base :

5729

SKU :

5729/10

product name :

TASP 0390325

units size :

10 mg (also 50 mg)

description :

Potent and selective V1B receptor antagonist; orally bioavailable

target :

Vasopressin Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

554.44

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TASP 0390325 is a potent and selective V1B receptor antagonist (IC50 = 2.22 nM for rat pituitary receptor). Exhibits no significant affinity for 85 other receptors, ion channels and transporters at 10 M, including V1A and V2. Increases ACTH levels in rats. Orally bioavailable. Antidepressant and anxiolytic.

top caption :

Potent and selective V1B receptor antagonist; orally bioavailable

extended description :

Potent and selective V1B receptor antagonist; orally bioavailable

chemical name text :

2-(3-Chloro-4-fluorophenyl)-N-(1-methylethyl)-6-[3-(4-morpholinyl)propoxy]-4-oxo-pyrido[2,3-d]pyrimidine-3(4H)-acetamide hydrochloride

formula :

C25H29ClFN5O4.HCl

formula text :

C25H29ClFN5O4.HCl

cas num :

1642187-96-9

USD :

278 USD

product details :

Potent and selective V1B receptor antagonist; orally bioavailable

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage