MC 1742 | Tocris Bioscience 5727 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MC 1742

catalog :

5727

quantity :

10 mg

price :

257 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5727

SKU :

5727/10

product name :

MC 1742

description :

Potent class I and IIb HDAC inhibitor

target :

Class I Histone Deacetylases Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

395.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent class I and IIb HDAC inhibitor (IC50 values are 7, 20, 40, 100, 110 and 610 nM for HDAC6, HDAC3, HDAC10, HDAC1, HDAC2 and HDAC8, respectively). Suppresses proliferation and induces apoptosis of sarcoma cancer stem cells (CSCs) at concentrations 500 nM. Also induces osteogenesis in sarcoma CSCs at concentrations of 25 - 500 nM .

catalog number base :

5727

product keywords :

MC1742 HDAC1 HDAC2 HDAC3 HDAC6 HDAC8 HDAC10 inhibitors inhibits histone deacetylases class II IIa epigenetics cancer stem cells CSCs osteogenic differentiation Cancer Stem Cells Class I HDACs Class II HDACs 5727,

extended description :

Potent class I and IIb HDAC inhibitor

chemical name text :

5-[(4-[1,1 -Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide

formula :

C 21 H 21 N 3 O 3 S

formula text :

C21H21N3O3S

cas num :

1776116-74-5

2020 USD :

249

2021 USD :

257 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage