product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
MC 1742
catalog :
5727/10
quantity :
10 mg
price :
323 USD
more info or order :
Tocris Bioscience product webpage
image
image 1 :
Tocris Bioscience 5727/10 image 1
Cat.No. 5727 - MC 1742 C21H21N3O3S CAS No. 1776116-74-5
product information
brand :
Tocris
catalog number base :
5727
SKU :
5727/10
product name :
MC 1742
units size :
10 mg
description :
Potent class I and IIb HDAC inhibitor
target :
Class I Histone Deacetylases Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
395.47
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
MC 1742 is a potent class I and IIb HDAC inhibitor (IC50 values are 7, 20, 40, 100, 110 and 610 nM for HDAC6, HDAC3, HDAC10, HDAC1, HDAC2 and HDAC8, respectively). Suppresses proliferation and induces apoptosis of sarcoma cancer stem cells (CSCs) at concentrations 500 nM. Also induces osteogenesis in sarcoma CSCs at concentrations of 25 - 500 nM .
top caption :
Potent class I and IIb HDAC inhibitor
extended description :
Potent class I and IIb HDAC inhibitor
chemical name text :
5-[(4-[1,1 -Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide
formula :
C21H21N3O3S
formula text :
C21H21N3O3S
cas num :
1776116-74-5
USD :
323 USD
product details :
Potent class I and IIb HDAC inhibitor
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK