MC 1742 | Tocris Bioscience 5727/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MC 1742

catalog :

5727/10

quantity :

10 mg

price :

323 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5727 - MC 1742 C21H21N3O3S CAS No. 1776116-74-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5727

SKU :

5727/10

product name :

MC 1742

description :

Potent class I and IIb HDAC inhibitor

target :

Class I Histone Deacetylases Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

395.47

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MC 1742 is a potent class I and IIb HDAC inhibitor (IC50 values are 7, 20, 40, 100, 110 and 610 nM for HDAC6, HDAC3, HDAC10, HDAC1, HDAC2 and HDAC8, respectively). Suppresses proliferation and induces apoptosis of sarcoma cancer stem cells (CSCs) at concentrations 500 nM. Also induces osteogenesis in sarcoma CSCs at concentrations of 25 - 500 nM .

product keywords :

MC1742 HDAC1 HDAC2 HDAC3 HDAC6 HDAC8 HDAC10 inhibitors inhibits histone deacetylases class II IIa epigenetics cancer stem cells CSCs osteogenic differentiation Cancer Stem Cells Class I HDACs Class II HDACs 5727,

extended description :

Potent class I and IIb HDAC inhibitor

chemical name text :

5-[(4-[1,1 -Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide

formula :

C21H21N3O3S

formula text :

C21H21N3O3S

cas num :

1776116-74-5

USD :

319

USD 2025 :

323 USD

product details :

Potent class I and IIb HDAC inhibitor

more info or order :

Tocris Bioscience product webpage