(+/-)-ADX 71743 | Tocris Bioscience 5715 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(+/-)-ADX 71743

catalog :

5715

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5715

SKU :

5715/10

product name :

(+/-)-ADX 71743

description :

Negative allosteric modulator of mGlu7 receptors; brain penetrant

target :

Group III mGluR Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

269.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Negative allosteric modulator at mGlu7 (IC50 = 300 nM). Blocks high frequency-induced LTP at SC-CA1 synapses in hippocampal slices in vitro . Increases evoked excitatory postsynaptic currents (eEPSCs) in mice. Brain penetrant.

catalog number base :

5715

product keywords :

(?)-ADX 71743 potent negative allosteric modulators NAMs mGlu7 receptors metabotropic glutamate epilepsy 1431641-29-0 Glutamate (Metabotropic) Group III Receptors 5715,

extended description :

Negative allosteric modulator of mGlu7 receptors; brain penetrant

chemical name text :

6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone

formula :

C 17 H 19 NO 2

formula text :

C17H19NO2

2020 USD :

185

2021 USD :

189 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage