MS 023 dihydrochloride | Tocris Bioscience 5713 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MS 023 dihydrochloride

catalog :

5713

quantity :

10 mg (also 50 mg)

price :

259 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Choucair A, Pham T, Omarjee S, Jacquemetton J, Kassem L, Tredan O, et al. The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer. Oncogene. 2019;38:4015-4027 pubmed publisher

product information

brand :

Tocris

master code :

5713

SKU :

5713/10

product name :

MS 023 dihydrochloride

description :

Potent and selective type I PRMT inhibitor

target :

Protein Arginine Methyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

360.32

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective type I PRMT inhibitor (IC50 values are 8, 8, 30, 83 and 119 nM for PRMT6, PRMT8, PRMT1, PRMT4 and PRMT3, respectively). Exhibits no significant activity against type II and III PRMTs, PKMTs, DNMTs, KDMs and reader proteins. Reduces global arginine asymmetric dimethylation levels in vitro .

catalog number base :

5713

product keywords :

MS023 dihydrochloride potent Type-1 selective PRMT inhibitors inhibits PRMT6 PRMT8 PRMT1 PRMT4 PRMT3 Protein Arginine Methyltransferases 5713,

extended description :

Potent and selective type I PRMT inhibitor

chemical name text :

N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride

formula :

C 17 H 25 N 3 O.2HCl

formula text :

C17H25N3O.2HCl

cas num :

1992047-64-9

2020 USD :

249

2021 USD :

259 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage