RA 839 | Tocris Bioscience 5707/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

RA 839

catalog :

5707/10

quantity :

10 mg (also 50 mg)

price :

296 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Zeb A, Choubey V, Gupta R, Kuum M, Safiulina D, Vaarmann A, et al. A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy. Redox Biol. 2021;48:102186 pubmed publisher
Patra U, Mukhopadhyay U, Mukherjee A, Sarkar R, Chawla Sarkar M. Progressive Rotavirus Infection Downregulates Redox-Sensitive Transcription Factor Nrf2 and Nrf2-Driven Transcription Units. Oxid Med Cell Longev. 2020;2020:7289120 pubmed publisher

image

image 1 :

Cat.No. 5707 - RA 839 C25H28N2O4S CAS No. 1832713-02-6

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5707

SKU :

5707/10

product name :

RA 839

description :

Nrf2 activator; inhibits Nrf2/Keap1 interaction

target :

Nrf2 Activators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

452.57

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

RA 839 is an Nrf2 activator; inhibits Nrf2/Keap1 interaction (Kd = 6 M). Suppresses LPS-induced iNOS and nitric oxide expression in macrophages. Anti-inflammatory.

product keywords :

RA839 Nrf2 activators activates NFE2L2 erythroid-derived nuclear factors Keap1 interations inhibitors inhibits inducible nitric oxide synthases nitric oxides anti-inflammatory Nrf2 5707,

extended description :

Nrf2 activator; inhibits Nrf2/Keap1 interaction

chemical name text :

(3S)-1-[4-[[(2,3,5,6-Tetramethylphenyl)sulfonyl]amino]-1-naphthalenyl]-3-pyrrolidinecarboxylic acid

formula :

C25H28N2O4S

formula text :

C25H28N2O4S

cas num :

1832713-02-6

USD :

293

USD 2025 :

296 USD

product details :

Nrf2 activator; inhibits Nrf2/Keap1 interaction

more info or order :

Tocris Bioscience product webpage