BAY 678 | Tocris Bioscience 5706 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 678

catalog :

5706

quantity :

25 mg

price :

308 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5706

SKU :

5706/25

product name :

BAY 678

description :

Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor

target :

Synthetic Elastase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

400.35

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM). Exhibits around 2000-fold selectivity for NHE against a panel of 21 other serine proteases. Effective in an acute lung injury model in vivo . Orally bioavailable. Inactive S-enantiomer (Cat.No.6389) also available.

catalog number base :

5706

product keywords :

BAY678 human neutrophil elastase inhibitors inhibits HNE orally bioavailable cell permeable potent selective Elastase 5706,

extended description :

Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor

chemical name text :

5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile

formula :

C 20 H 15 F 3 N 4 O 2

formula text :

C20H15F3N4O2

cas num :

675103-36-3

2020 USD :

301

2021 USD :

308 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage