BAY 678 | Tocris Bioscience 5706/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 678

catalog :

5706/5

quantity :

5 mg (also 25 mg)

price :

94 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5706 - BAY 678 C20H15F3N4O2 CAS No. 675103-36-3

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5706

SKU :

5706/5

product name :

BAY 678

description :

Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor

target :

Synthetic Elastase Inhibitors

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

400.35

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BAY 678 is a potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM). Exhibits around 2000-fold selectivity for NHE against a panel of 21 other serine proteases. Effective in an acute lung injury model in vivo . Orally bioavailable. Inactive S-enantiomer (Cat.No.6389) also available.

product keywords :

BAY678 human neutrophil elastase inhibitors inhibits HNE orally bioavailable cell permeable potent selective Elastase 5706,

extended description :

Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor

chemical name text :

5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile

formula :

C20H15F3N4O2

formula text :

C20H15F3N4O2

cas num :

675103-36-3

USD :

USD 2025 :

94 USD

product details :

Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor

more info or order :

Tocris Bioscience product webpage