AMG 853 | Tocris Bioscience 5701/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AMG 853

catalog :

5701/10

quantity :

10 mg

price :

358 USD

product information

brand :

Tocris

master code :

5701

SKU :

5701/10

product name :

AMG 853

unit size :

10 mg

seo description :

Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist

target :

Prostanoid Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

609.49

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AMG 853 is a potent prostaglandin D2 (PGD2, CRTH2) receptor antagonist (IC50 values are 8 and 35 nM, respectively in plasma). Inhibits PGD2-induced down modulation of CRTH2 on CD16- granulocytes in human whole blood as well as PGD2-induced cAMP response in platelets. Inhibits PGD2-induced airway constriction in vivo . Orally bioavailable.

top caption :

Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist

extended description :

Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist

chemical name text :

5-Chloro-4-[2-[[(2-chloro-4-cyclopropylphenyl)sulfonyl]amino]-4-[[(1,1-dimethylethyl)amino]carbonyl]phenoxy]-2-fluorobenzeneacetic acid

formula :

C28H27Cl2FN2O6S

formula text :

C28H27Cl2FN2O6S

cas num :

1169483-24-2

USD :

358 USD

product details :

Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist

storage :

Store at -20░C