GSK 2033 | Tocris Bioscience 5694 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 2033

catalog :

5694

quantity :

10 mg (also 50 mg)

price :

216 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Bruschi F, Claudel T, Tardelli M, Starlinger P, Marra F, Trauner M. PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells. Hepatol Commun. 2019;3:1191-1204 pubmed publisher
Hutchinson S, Lianto P, Moore J, Hughes T, Thorne J. Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells. Int J Mol Sci. 2019;20: pubmed publisher
Bonney S, Siegenthaler J. Differential Effects of Retinoic Acid Concentrations in Regulating Blood-Brain Barrier Properties. Eneuro. 2017;4: pubmed publisher
Solt L, Kamenecka T, Burris T. LXR-mediated inhibition of CD4+ T helper cells. PLoS ONE. 2012;7:e46615 pubmed publisher

product information

brand :

Tocris

master code :

5694

SKU :

5694/10

product name :

GSK 2033

description :

Potent LXR antagonist

target :

LXR-like Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

591.66

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent LXR antagonist (pIC50 = 7.5). Enhances T-cell proliferation and blocks T 0901317 -antiproliferative activity on T-cells. Cell permeable.

catalog number base :

5694

product keywords :

GSK2033 Potent LXR antagonists liver x receptors LXR-like Receptors 5694,

extended description :

Potent LXR antagonist

chemical name text :

2,4,6-Trimethyl-N-[[3 -(methylsulfonyl)[1,1 -biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide

formula :

C 29 H 28 F 3 NO 5 S

formula text :

C29H28F3NO5S

cas num :

1221277-90-2

2020 USD :

207

2021 USD :

216 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage