VU 0409551 | Tocris Bioscience 5693 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0409551

catalog :

5693

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5693

SKU :

5693/10

product name :

VU 0409551

description :

Selective positive allosteric modulator of mGlu5 receptors; brain penetrant and orally bioavailable

target :

Group I mGluR Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

352.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective mGlu5 positive allosteric modulator (EC50 = 260 nM). Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu5 signaling via G q. Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available.

catalog number base :

5693

product keywords :

JNJ46778212 VU0409551 metabotropic glutamate receptors mGlu5 positive allosteric modulators modulates PAMs JNJ 46778212 Glutamate (Metabotropic) Group I Receptors 5693,

extended description :

Selective positive allosteric modulator of mGlu5 receptors; brain penetrant and orally bioavailable

chemical name text :

[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone

formula :

C 20 H 17 FN 2 O 3

formula text :

C20H17FN2O3

cas num :

1363281-27-9

2020 USD :

197

2021 USD :

205 USD

alt names :

JNJ 46778212

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage