VU 0409551 | Tocris Bioscience 5693/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0409551

catalog :

5693/10

quantity :

10 mg (also 50 mg)

price :

263 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5693 - VU 0409551 C20H17FN2O3 CAS No. 1363281-27-9

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5693

SKU :

5693/10

product name :

VU 0409551

description :

Selective positive allosteric modulator of mGlu5 receptors; brain penetrant and orally bioavailable

target :

Group I mGluR Modulators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

352.36

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VU 0409551 is a selective mGlu5 positive allosteric modulator (EC50 = 260 nM). Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu5 signaling via G q. Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available.

product keywords :

JNJ46778212 VU0409551 metabotropic glutamate receptors mGlu5 positive allosteric modulators modulates PAMs JNJ 46778212 Glutamate (Metabotropic) Group I Receptors 5693,

extended description :

Selective positive allosteric modulator of mGlu5 receptors; brain penetrant and orally bioavailable

chemical name text :

[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone

formula :

C20H17FN2O3

formula text :

C20H17FN2O3

cas num :

1363281-27-9

USD :

255

USD 2025 :

263 USD

product details :

Selective positive allosteric modulator of mGlu5 receptors; brain penetrant and orally bioavailable

alt names :

JNJ 46778212

more info or order :

Tocris Bioscience product webpage