product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ITH 12575
catalog :
5692
quantity :
10 mg (also 50 mg)
price :
207 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
5692
SKU :
5692/10
product name :
ITH 12575
description :
Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor
target :
Na+/Ca2+ Exchanger Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
331.86
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor. Reduces Ca2+ efflux from the mitochondria to the cytosol in HeLa cells (EC50 = 0.69 M). Protects against glutamate-induced excitotoxitiy in rat hippocampal slices and oligomycin A/rotenone induced oxidative stress in neuroblastoma cells in vitro .
catalog number base :
5692
product keywords :
ITH12575 sodium calcium exchangers inhibitors inhibits Na+ Ca2+ exchange neuroprotectant neuroprotection mitochondrial mNCX Na+/Ca2+ Exchanger 5692,
extended description :
Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor
chemical name text :
7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one
formula :
C 18 H 18 ClNOS
formula text :
C18H18ClNOS
cas num :
1802013-08-6
2020 USD :
207
2021 USD :
207 USD
storage :
Store at RT
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK