ITH 12575 | Tocris Bioscience 5692/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ITH 12575

catalog :

5692/10

quantity :

10 mg (also 50 mg)

price :

260 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5692

SKU :

5692/10

product name :

ITH 12575

description :

Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor

target :

Na+/Ca2+ Exchanger Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

331.86

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ITH 12575 is a mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor. Reduces Ca2+ efflux from the mitochondria to the cytosol in HeLa cells (EC50 = 0.69 M). Protects against glutamate-induced excitotoxitiy in rat hippocampal slices and oligomycin A/ rotenone induced oxidative stress in neuroblastoma cells in vitro .

product keywords :

ITH12575 sodium calcium exchangers inhibitors inhibits Na+ Ca2+ exchange neuroprotectant neuroprotection mitochondrial mNCX Na+/Ca2+ Exchanger 5692,

extended description :

Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor

chemical name text :

7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one

formula :

C18H18ClNOS

formula text :

C18H18ClNOS

cas num :

1802013-08-6

USD :

257

USD 2025 :

260 USD

product details :

Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor