Centrinone | Tocris Bioscience 5687/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Centrinone

catalog :

5687/10

quantity :

10 mg

price :

301 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5687

SKU :

5687/10

rank :

0.061

product name :

Centrinone

description :

High affinity and selective PLK4 inhibitor

target :

Polo-like Kinase Inhibitors

category :

Small Molecules

sizes available :

10 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Centrinone is a high affinity and selective PLK4 inhibitor (Ki = 0.16 nM). Exhibits 1000-fold selectivity for PLK4 over Aurora A and Aurora B. Depletes centriole and centrosome levels in vitro . Induces cell cycle arrest in normal human cell lines in a p53-dependent manner. Decreases expression of pluripotency markers and induces differentiation in pluripotent stem cells.

extended description :

High affinity and selective PLK4 inhibitor

chemical name text :

2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine

formula :

C 26 H 25 F 2 N 7 O 6 S 2

formula text :

C26H25F2N7O6S2

cas num :

1798871-30-3

USD :

301 USD

product details :

High affinity and selective PLK4 inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage