OSU 03012 | Tocris Bioscience 5682 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

OSU 03012

catalog :

5682

quantity :

10 mg (also 50 mg)

price :

154 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5682

SKU :

5682/10

product name :

OSU 03012

description :

PDPK1 (PDK1) inhibitor; inhibits Akt signaling

target :

PDK-1 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

460.45

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PDPK1 (PDK1) inhibitor; inhibits Akt signaling. Induces apoptosis of PC-3 and medulloblastoma cells, and inhibits growth of a number of tumor cell lines. Sensitizes radiotherapy-induced cell death and enhances cytotoxic effects of chemotherapeutic agents in vitro . Attenuates tumor growth of medulloblastoma xenografts in mice.

catalog number base :

5682

product keywords :

OSU03012 PDK1 Akt antitumor anticancer 3-phospho-inositide-dependent kinases-1 PDPK1 Phosphoinositide-dependent Kinase 1 PDK1 Akt (Protein Kinase B) Protein Kinase B/Akt 5682,

extended description :

PDPK1 (PDK1) inhibitor; inhibits Akt signaling

chemical name text :

2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide

formula :

C 26 H 19 F 3 N 4 O

formula text :

C26H19F3N4O

cas num :

742112-33-0

2020 USD :

154

2021 USD :

154 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage