Vatalanib succinate | Tocris Bioscience 5680 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Vatalanib succinate

catalog :

5680

quantity :

10 mg (also 50 mg)

price :

117 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rasmussen J, Vo N, Sagasti A. Fish Scales Dictate the Pattern of Adult Skin Innervation and Vascularization. Dev Cell. 2018;46:344-359.e4 pubmed publisher

product information

brand :

Tocris

master code :

5680

SKU :

5680/10

product name :

Vatalanib succinate

description :

Potent VEGFR inhibitor; also aromatase inhibitor

target :

VEGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

464.9

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent VEGFR inhibitor (IC50 values are 37 and 77 nM for VEGFR-2 and -1, respectively). Inhibits proliferation, migration and survival of HUVECs in vitro and inhibits growth, vascularization and metastasis of tumors expressing VEGFR in mouse models. Also inhibits PDGFR- , c-Kit and c-Fms. Potent aromatase inhibitor (IC50 = 50 nM). Orally available.

catalog number base :

5680

product keywords :

CGP79787D PTK787 ZK222584 aromatase inhibitors inhibits vascular endothelial growth factor receptors tyrosine kinases cancer anticancer VEGFR angiogenesis metastasis CGP 79787D PTK787/ZK222584 VEGFR Cytochrome P450 5680, VEGFR, VEGF R

extended description :

Potent VEGFR inhibitor; also aromatase inhibitor

chemical name text :

N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate

formula :

C 20 H 15 ClN 4 .C 4 H 6 O 4

formula text :

C20H15ClN4.C4H6O4

cas num :

212142-18-2

2020 USD :

129

2021 USD :

117 USD

alt names :

CGP 79787D, PTK787/ZK222584

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage