Vatalanib succinate | Tocris Bioscience 5680/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Vatalanib succinate

catalog :

5680/10

quantity :

10 mg (also 50 mg)

price :

132 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Bump R, Goo C, Horton E, Rasmussen J. Osteoblasts pattern endothelium and somatosensory axons during zebrafish caudal fin organogenesis. Development. 2022;149: pubmed publisher
Rasmussen J, Vo N, Sagasti A. Fish Scales Dictate the Pattern of Adult Skin Innervation and Vascularization. Dev Cell. 2018;46:344-359.e4 pubmed publisher

image

image 1 :

Cat.No. 5680 - Vatalanib succinate C20H15ClN4.C4H6O4 CAS No. 212142-18-2

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5680

SKU :

5680/10

product name :

Vatalanib succinate

description :

Potent VEGFR inhibitor; also aromatase inhibitor

target :

VEGF Receptor Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at -20°C

observed molecular weight :

464.9

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Vatalanib succinate is a potent VEGFR inhibitor (IC50 values are 37 and 77 nM for VEGFR-2 and -1, respectively). Inhibits proliferation, migration and survival of HUVECs in vitro and inhibits growth, vascularization and metastasis of tumors expressing VEGFR in mouse models. Also inhibits PDGFR- , c-Kit and c-Fms. Potent aromatase inhibitor (IC50 = 50 nM). Orally available.

product keywords :

CGP79787D PTK787 ZK222584 aromatase inhibitors inhibits vascular endothelial growth factor receptors tyrosine kinases cancer anticancer VEGFR angiogenesis metastasis CGP 79787D PTK787/ZK222584 VEGFR Cytochrome P450 5680, VEGFR, VEGF R

extended description :

Potent VEGFR inhibitor; also aromatase inhibitor

chemical name text :

N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate

formula :

C20H15ClN4.C4H6O4

formula text :

C20H15ClN4.C4H6O4

cas num :

212142-18-2

USD :

146

USD 2025 :

132 USD

product details :

Potent VEGFR inhibitor; also aromatase inhibitor

alt names :

CGP 79787D,PTK787/ZK222584

more info or order :

Tocris Bioscience product webpage