Guangxitoxin 1E | Tocris Bioscience 5676/100U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Guangxitoxin 1E

catalog :

5676/100U

quantity :

100 ug

price :

374 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Kim H, Li H, Kim H, Shin S, Seo M, An J, et al. Escitalopram, a selective serotonin reuptake inhibitor, inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Korean J Physiol Pharmacol. 2017;21:415-421 pubmed publisher

image

image 1 :

Cat.No. 5676 - Guangxitoxin 1E Glu-Gly-Glu-Cys-Gly-Gly-Phe-Trp-Trp-Lys-Cys-Gly-Ser-Gly-Lys-Pro-Ala-Cys-Cys-Pro-Lys-Tyr-Val-Cys-Ser-Pro-Lys-Trp-Gly-Leu-Cys-Asn-Phe-Pro-Met-Pro (Disulfide bridges: 4-19, 11-24, 18-31) CAS No. 1233152-82-3

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5676

SKU :

5676/100U

product name :

Guangxitoxin 1E

description :

Potent Kv2.1 and Kv2.2 channel blocker

target :

Voltage-gated Potassium Channel Blockers

unit size :

100 ug

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

3948.61

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Guangxitoxin 1E is a Kv2.1 and Kv2.2 channel blocker (IC50 values are 1-3 nM). Enhances glucose-stimulated insulin secretion from human islets in vitro , but not from islet cells lacking the Kv2.1 channel. Has no significant effect on plasma insulin, glucagon or blood glucose levels in mice, but increases plasma somatostatin levels.

product keywords :

Kv2.1 Kv2.2 inward rectifier potassium current pancreatic islets beta cells inhibits inhibitors insulin glucose somatostatin GxTx-1E venoms Voltage-Gated Potassium Channels 5676,

extended description :

Potent Kv2.1 and Kv2.2 channel blocker

formula :

C178H248N44O45S7

formula text :

C178H248N44O45S7

cas num :

1233152-82-3

USD :

363

USD 2025 :

374 USD

product details :

Potent Kv2.1 and Kv2.2 channel blocker

more info or order :

Tocris Bioscience product webpage