SB 332235 | Tocris Bioscience 5671/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 332235

catalog :

5671/10

quantity :

10 mg (also 50 mg)

price :

269 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5671 - SB 332235 C13H10Cl3N3O4S CAS No. 276702-15-9

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5671

SKU :

5671/10

product name :

SB 332235

description :

Potent CXCR2 antagonist

target :

Chemokine Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

410.66

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 332235 is a potent CXCR2 antagonist (IC50 = 7.7 nM). Exhibits 285-fold selectivity for CXCR2 over CXCR1. Reduces leukocyte numbers in synovial fluid in acute and chronic rabbit arthritis models. Also reduces synovial fluid eicosanoid and cytokine levels in a rabbit chronic arthritis model. Inhibits proliferation of AML cell lines in vitro .

product keywords :

SB332235 chemokines receptors CXCR2 interleukin-8 IL-8 inflammation chronic acute rheumatoid arthritis antagonists antagonism Chemokine CXC Receptors 5671,

extended description :

Potent CXCR2 antagonist

chemical name text :

6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide

formula :

C13H10Cl3N3O4S

formula text :

C13H10Cl3N3O4S

cas num :

276702-15-9

USD :

266

USD 2025 :

269 USD

product details :

Potent CXCR2 antagonist

more info or order :

Tocris Bioscience product webpage