product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ONO 6818
catalog :
5651
quantity :
10 mg
price :
252 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
5651
SKU :
5651/10
product name :
ONO 6818
description :
High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active
target :
Synthetic Elastase Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
452.51
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor (Ki = 12 nM). Exhibits 100-fold less activity at other related proteases including trypsin, pancreatic elastase, collagenase and murine macrophage elastase. Inhibits HNE-induced lung hemorrhaging and suppresses leukocyte levels in an in vivo model of COPD. Orally active.
catalog number base :
5651
product keywords :
ONO6818 High affinity selective human neutraphil elastases 1 HNE1 inhibitors inhibits COPD chronic obstructive pulmonary disease colitis orally active Elastase 5651,
extended description :
High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active
chemical name text :
5-Amino-N-[1-[[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]carbonyl]-2-methylpropyl]-6-oxo-2-phenyl-1(6H)-pyrimidineacetamide
formula :
C 23 H 28 N 6 O 4
formula text :
C23H28N6O4
cas num :
208848-19-5
2020 USD :
244
2021 USD :
252 USD
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK