ONO 6818 | Tocris Bioscience 5651/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ONO 6818

catalog :

5651/10

quantity :

10 mg

price :

317 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5651 - ONO 6818 C23H28N6O4 CAS No. 208848-19-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5651

SKU :

5651/10

product name :

ONO 6818

description :

High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active

target :

Synthetic Elastase Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

452.51

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ONO 6818 is a high affinity and selective human neutrophil elastase 1 (HNE1) inhibitor (Ki = 12 nM). Exhibits 100-fold less activity at other related proteases including trypsin, pancreatic elastase, collagenase and murine macrophage elastase. Inhibits HNE-induced lung hemorrhaging and suppresses leukocyte levels in an in vivo model of COPD. Orally active.

product keywords :

ONO6818 High affinity selective human neutraphil elastases 1 HNE1 inhibitors inhibits COPD chronic obstructive pulmonary disease colitis orally active Elastase 5651,

extended description :

High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active

chemical name text :

5-Amino-N-[1-[[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]carbonyl]-2-methylpropyl]-6-oxo-2-phenyl-1(6H)-pyrimidineacetamide

formula :

C23H28N6O4

formula text :

C23H28N6O4

cas num :

208848-19-5

USD :

313

USD 2025 :

317 USD

product details :

High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active

more info or order :

Tocris Bioscience product webpage