Hydroxychloroquine sulfate | Tocris Bioscience 5648/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Hydroxychloroquine sulfate

catalog :

5648/10

quantity :

10 mg (also 50 mg)

price :

114 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lee H, Mustafa A, Hudes G, Kruger W. Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS ONE. 2015;10:e0131464 pubmed publisher

product information

brand :

Tocris

master code :

5648

SKU :

5648/10

rank :

0.071

product name :

Hydroxychloroquine sulfate

description :

Autophagy inhibitor; also TLR9 inhibitor

target :

Autophagy-related Compounds

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Hydroxychloroquine sulfate is an autophagy inhibitor. Also inhibits TLR9. Inhibits growth and induces apoptosis of renal cancer cells in vitro . Additionally inhibits PRC2 by inhibiting the allosteric binding of PRC2 to EED (embryonic ectoderm development) within the H3K27me3-binding pocket, and reduces H3K27me3 levels in multiple myeloma cells in vitro . Inhibits SARS-CoV-2 viral infection, in vitro (EC50 values in M range and dependent on viral RNA copy number). Hydroxychloroquine improves efficacy of adeno-associated viral gene transduction in vivo and in vitro . Also antimalarial and immunomodulator. . Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

extended description :

Autophagy inhibitor; also TLR9 inhibitor

chemical name text :

2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate

formula :

C 18 H 28 ClN 3 O 5 S

formula text :

C18H28ClN3O5S

cas num :

747-36-4

USD :

114 USD

product details :

Autophagy inhibitor; also TLR9 inhibitor

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage