MI 192 | Tocris Bioscience 5647 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MI 192

catalog :

5647

quantity :

10 mg

price :

174 USD

citations: 1

Reference
Martin J, Werner C, Mitra S, Zhong P, Wang Z, Gobira P, et al. A novel role for the actin-binding protein drebrin in regulating opiate addiction. Nat Commun. 2019;10:4140 pubmed publisher

product information

brand :

Tocris

master code :

5647

SKU :

5647/10

product name :

MI 192

description :

Potent and selective HDAC2/3 inhibitor

target :

Class I Histone Deacetylases Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

383.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective HDAC2/3 inhibitor (IC50 values are 16 and 30 nM, respectively). Exhibits 250-fold selectivity for HDAC2/3 over other HDAC isoforms. Promotes apoptosis of leukemia cell lines in vitro . Also attenuates IL-6 production in rheumatoid arthritis PBMCs in vitro .

catalog number base :

5647

product keywords :

MI192 potent selective HDAC2 HDAC3 histones deacetylases Class I HDACs 5647,

extended description :

Potent and selective HDAC2/3 inhibitor

chemical name text :

N-(2-Aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]benzamide

formula :

C 24 H 21 N 3 O 2

formula text :

C24H21N3O2

cas num :

1415340-63-4

2020 USD :

168

2021 USD :

174 USD

storage :

Store at -20°C