CMPD101 | Tocris Bioscience 5642/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CMPD101

catalog :

5642/10

quantity :

10 mg

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Reyes Alcaraz A, Lee Y, Yun S, Hwang J, Seong J. Conformational signatures in β-arrestin2 reveal natural biased agonism at a G-protein-coupled receptor. Commun Biol. 2018;1:128 pubmed publisher

product information

brand :

Tocris

master code :

5642

SKU :

5642/10

rank :

0.061

product name :

CMPD101

description :

Potent and selective GRK2/3 inhibitor

target :

G Protein (Heterotrimeric) Inhibitors

category :

Small Molecules

sizes available :

10 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CMPD101 is a potent and selective GRK2/3 inhibitor (IC50 values are 32 and 54 nM for GRK3 and GRK2, respectively). Exhibits selectivity for GRK2/3 over GRK1/5. Reduces DAMGO -induced desensitization and internalization of -opioid receptors.

extended description :

Potent and selective GRK2/3 inhibitor

chemical name text :

3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide

formula :

C 24 H 21 F 3 N 6 O

formula text :

C24H21F3N6O

cas num :

865608-11-3

USD :

191 USD

product details :

Potent and selective GRK2/3 inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage