MSC 2032964A | Tocris Bioscience 5641 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MSC 2032964A

catalog :

5641

quantity :

10 mg (also 50 mg)

price :

221 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5641

SKU :

5641/10

product name :

MSC 2032964A

description :

Potent and selective ASK1 inhibitor; orally bioavailable

target :

ASK1 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

362.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective ASK1 inhibitor (IC50 = 93 nM). Selective for ASK1 over a panel of 210 kinases. Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. Suppresses neuroinflammation in a mouse EAE model. Orally bioavailable and brain penetrant.

catalog number base :

5641

product keywords :

MSC2032964A apoptosis signal regulating kinase 1 ASK1 inhibits inhibitors potent selective orally bioavailable neuroinflammation EAE experimental autoimmune encephalomyelitis ASK1 5641,

extended description :

Potent and selective ASK1 inhibitor; orally bioavailable

chemical name text :

N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide

formula :

C 16 H 13 F 3 N 6 O

formula text :

C16H13F3N6O

cas num :

1124381-43-6

2020 USD :

212

2021 USD :

221 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage