AZ Dyrk1B 33 | Tocris Bioscience 5632 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZ Dyrk1B 33

catalog :

5632

quantity :

10 mg

price :

296 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5632

SKU :

5632/10

product name :

AZ Dyrk1B 33

description :

Potent and selective Dyrk1B kinase inhibitor

target :

DYRK Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

300.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective ATP-competitive Dyrk1B kinase inhibitor (IC50 = 7 nM); displays distinct cellular effects when compared to DYRK1B knockdown through siRNA. Demonstrates cellular in vitro activity (IC50 = 194 nM). Exhibits better selectivity than AZ 191 (Cat. No 5232); displays no off-target effects against a panel of 124 kinases tested (no kinase was inhibited above 50% at 1 M).

catalog number base :

5632

product keywords :

AZDyrk1B33 Dyrk1B kinase inhibitors inhibits dual specificity tyrosine phosphorylation regulated kinases potent DYRK 5632,

extended description :

Potent and selective Dyrk1B kinase inhibitor

chemical name text :

3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine

formula :

C 19 H 16 N 4

formula text :

C19H16N4

cas num :

1679330-37-0

2020 USD :

284

2021 USD :

296 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage