HTH 01-015 | Tocris Bioscience 5622 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HTH 01-015

catalog :

5622

quantity :

10 mg (also 50 mg)

price :

203 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5622

SKU :

5622/10

product name :

HTH 01-015

description :

Potent and selective NUAK1 inhibitor

target :

NUAK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

468.55

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective NUAK1 inhibitor (IC50 = 100 nM). Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members. Inhibits NUAK1-mediated MYPT1 phosphorylation. Also inhibits cell proliferation in U2OS cells in vitro , to a similar extent as NUAK1 knockdown models.

catalog number base :

5622

product keywords :

HTH01-015 potent selective NUAK1 family SNF1-like kinase-1 inhibitors inhibits NUAK 5622,

extended description :

Potent and selective NUAK1 inhibitor

chemical name text :

5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one

formula :

C 26 H 28 N 8 O

formula text :

C26H28N8O

cas num :

1613724-42-7

2020 USD :

195

2021 USD :

203 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage