HTH 01-015 | Tocris Bioscience 5622/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HTH 01-015

catalog :

5622/10

quantity :

10 mg (also 50 mg)

price :

228 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5622 - HTH 01-015 C26H28N8O CAS No. 1613724-42-7

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5622

SKU :

5622/10

product name :

HTH 01-015

description :

Potent and selective NUAK1 inhibitor

target :

NUAK Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

468.55

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

HTH 01-015 is a potent and selective NUAK1 inhibitor (IC50 = 100 nM). Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members. Inhibits NUAK1-mediated MYPT1 phosphorylation. Also inhibits cell proliferation in U2OS cells in vitro , to a similar extent as NUAK1 knockdown models.

product keywords :

HTH01-015 potent selective NUAK1 family SNF1-like kinase-1 inhibitors inhibits NUAK 5622,

extended description :

Potent and selective NUAK1 inhibitor

chemical name text :

5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one

formula :

C26H28N8O

formula text :

C26H28N8O

cas num :

1613724-42-7

USD :

253

USD 2025 :

228 USD

product details :

Potent and selective NUAK1 inhibitor

more info or order :

Tocris Bioscience product webpage